Immune Response to Substituted Arsanilazo–Human Gamma Globulin Conjugates in Mice Tolerant to Human Gamma Globulin
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Sensitization to Denatured Autologous Gamma Globulin
Immunization of guinea pigs with denatured autologous gamma globulin results in the development of delayed hypersensitivity to some form of gamma globulin. When the autologous gamma globulin is subjected to denaturation with alkaline treatment as employed in this study, guinea pigs regularly develop reactivity to the immunizing material and occasionally to some form of heterologous gamma globul...
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ژورنال
عنوان ژورنال: Nature
سال: 1967
ISSN: 0028-0836,1476-4687
DOI: 10.1038/213496a0